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Early childhood is a sensitive period for learning and social skill development. The maturation of cerebral regions underlying social processing lays the foundation for later social-emotional competence. This study explored myelin changes in social brain regions and their association with changes in parent-rated social-emotional development in a cohort of 129 children (64 females, 0–36 months, 77 White). Results reveal a steep increase in myelination throughout the social brain in the first 3 years of life that is significantly associated with social-emotional development scores. These findings add knowledge to the emerging picture of social brain development by describing neural underpinnings of human social behavior. They can contribute to identifying age-/stage-appropriate early life factors in this developmental domain.  相似文献   
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In this article we examine the complex relationship between care experience, mental health and exclusion from school and how young people (YP) negotiate these different experiences and identities. The study is a secondary analysis, informed by symbolic interactionist theory, of interviews conducted with 19 care experienced YP in Scotland. Not all of the YP were excluded and not all had a formal mental health diagnosis, as such our study design allows interrogation of the contexts and relationships which not only facilitate but also disrupt pathways to exclusion. It also allows reconsideration of assumptions of vulnerability which are often applied to care experienced YP. Our findings suggest that these YP are moving beyond ‘role playing’ the identities ascribed to them and actively seek out relationships which enable them to construct alternative identities.  相似文献   
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The value that willed body donors provide to medical education is priceless. Their precious gift helps to teach anatomy, spatial relationships between morphological structures, anatomical variation, and professionalism to medical students in a way that plastic models, podcasts, and lectures cannot. They are also an important resource for medical research and a wide variety of postgraduate training opportunities. While many body donation programs throughout the world are nonprofit organizations, there are body donation companies in the United States that sell donors for-profit. These “body brokers” have accumulated large profits from this business. It is incongruous that others would profit from such a priceless, freely donated gift. To prevent this incongruity, it is proposed that the international anatomical community develop a normative culture (a bioethos) for body donation programs. This would involve the conscious and systematic development of ethical principles for the day-to-day policies and practices of institutions that collect and use human bodies. With the development of this bioethos, a cultural shift in how donors are treated would occur and, over time, this would become the normal practice. These principles would become fundamental and foundational for the procurement and use of priceless human tissues.  相似文献   
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Although there has been a great deal of research into Collaborative Information Retrieval (CIR) and Collaborative Information Seeking (CIS), the majority has assumed that team members have the same level of unrestricted access to underlying information. However, observations from different domains (e.g. healthcare, business, etc.) have suggested that collaboration sometimes involves people with differing levels of access to underlying information. This type of scenario has been referred to as Multi-Level Collaborative Information Retrieval (MLCIR). To the best of our knowledge, no studies have been conducted to investigate the effect of awareness, an existing CIR/CIS concept, on MLCIR. To address this gap in current knowledge, we conducted two separate user studies using a total of 5 different collaborative search interfaces and 3 information access scenarios. A number of Information Retrieval (IR), CIS and CIR evaluation metrics, as well as questionnaires were used to compare the interfaces. Design interviews were also conducted after evaluations to obtain qualitative feedback from participants. Results suggested that query properties such as time spent on query, query popularity and query effectiveness could allow users to obtain information about team's search performance and implicitly suggest better queries without disclosing sensitive data. Besides, having access to a history of intersecting viewed, relevant and bookmarked documents could provide similar positive effect as query properties. Also, it was found that being able to easily identify different team members and their actions is important for users in MLCIR. Based on our findings, we provide important design recommendations to help develop new CIR and MLCIR interfaces.  相似文献   
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We analyse the evolution of the slope (critical speed) and the y-intercept (anaerobic distance capacity) of the linear distance-time relationship over a century of Olympic running performances. The distance-time relationship of each Olympic Games (1920-2004) was plotted using the performances in the 800-, 1500- and 5000-m track events. Values for critical speed and anaerobic distance capacity were determined by linear modelling. Mean performances for the 800, 1500 and 5000 m were 104.9 +/- 1.5 s (1.4%), 217.2 +/- 2.8 s (1.3%) and 808.9 +/- 18.4 s (2.3%), respectively. Critical speed improved during the first three-quarters of the twentieth century to reach a plateau in 1984. This is in accordance with the literature (Peronnet & Thibault, 1989) and suggests that "human aerobic endurance" has improved within the century (+13.4%) and tends to stabilize. Anaerobic distance capacity was highly variable over the century (coefficient of variation = 9.4%) and did not show a linear improvement over the years as has previously been suggested (Peronnet & Thibault, 1989). This could be due to an artefact in the application of the two-parameter model to only three Olympic performances. A limitation to the use of this linear mathematical model to fit physiological data may have been demonstrated.  相似文献   
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